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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb78a0215b0921c4834a826935f0dac78061b8607a3d6101f20c98104b4f001a' 
  AND token = '1Ec7pm2Nw/NIKys+8guJWP3UXeTRtHdFIQgy1B2tSyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}