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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edd746b17214f20f1bd563075f0661469e6d65ccc4da736d65ddc44ee355a6c5' 
  AND token = 'lvtLMeJ3IiZlEHoY3p3xpfG1y7vnzjz07eiDKFKClOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}