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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c03d49c3398b27a08b11160cb197c64a9c3ec086d13b276229d31f5da7a9d88' 
  AND token = '4d/4QRFq4LNetD0DKbFT86GmnHCHly47jwUPjIIr6Ek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}