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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c10aaa4355bc50b5d8f3d322c0c8707a7a1d41d39af7cce5152ffca8c6ad8291' 
  AND token = 'FneghUHwscVJoThlXtzSu2dUtnOu6NLGiV15QMlUZMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}