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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3c5a722d64fef4cc8e23e543eb2262f5771d0bd567ff2074e486ee287fb7ed1' 
  AND token = 'aqyyDVrbKVcyGh2Yk46mnmH6NAWuR7IAET03OiqWq+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}