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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e4ca0cda00fcb9aaabb7573f506828963e8beceee09fc6e59eb76ccda89a66f' 
  AND token = 'GMIGeTVWYQz3OdZ1pVrkR+p0HpRRvuA2l7NOlfOokLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}