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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8adfa500b7b6db80ae9c9eb899811e5bd16894a86be485822a50df70a32b31d0' 
  AND token = 'INaAdZaPbpzBwfRH1ivWX3+of3BcaSks6Lr3X96C0i8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}