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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c65d5c577f47c1c8c11734e3665f67a6c6a580909bf782c58d5e9a1d1c7f046' 
  AND token = 'xSYqUcSRRU480P9pVH7nft3qrtrxLzEtDIEakz9Qo3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}