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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '644038d9a926a802521ddf8cb710199e751c8e9137bb5cce73fa4d1598a014e2' 
  AND token = 'IZwUUyW9crtj+4oSUU8uO6NLCX5K2osybvIeNwzFEvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}