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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0651b0c386c55e56a3ab4e0c9598343eb12deb8e0cbabf05f32abdc1a29d0771' 
  AND token = 'i8m2ZkL5l3t0TNRgIi5GfAiN4tcVv2XgutKpQ7RrptY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}