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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9dfa1f88efa5234c7530901e1881ed7564dcff9b9a282d2e2f0cef9df08e476d' 
  AND token = 'Hcopp0Z3n/kOznif/bp27tgdFGZuEbDthdGVjywsTEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}