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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bd3721328eb3fcf545e6f9b21ef16d1b225ca9c739aad047df3fbb28cb4f075' 
  AND token = 'x6aYYYBCIu+B1fr2mZwU11GFUsXr2zbvrRhC6oH8ycM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}