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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a8c011f0b8fa247869117e4091016a021fc2df527c8798422f2d13262d46909' 
  AND token = 'nRdVZ1k2Ue5yfxZmUwphp1KaNzWCfJvf5U8kMdvmTQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}