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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f883f26041a0e26872f514e6017b41ec858b50004f7c47bc5e98807c3b24422a' 
  AND token = 'UWHynww6EKuHNxLGVM4L/iJySk4kRIlKYDWPCgBaHdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}