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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7fa12018899e1d1823517d64646507265a64efe5a8a9e341a695220c45f6519' 
  AND token = 'mi0vIDjPjkEGxiZFyez86vQOlIYgMZ1BT1TYiZz55jM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}