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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ac5a71270c096ca22b0152c0c2b57d83a4d7971ceefcfd40c1e15879e32285d' 
  AND token = 'afmjts2/EkFz1a/+7L/dUiDmQW3Q9K6S933iKguqzJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}