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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '347dc77abe6345f13600e1ecc97f9acb1627658e26d74e69b2f7c030fa9e7bd5' 
  AND token = '9wuOTXfTLxAFRm1Uiu67nYznv1xm1ovRSc3Em58KzPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}