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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72b3ccb2729c9495dd8ee16fd7fa4010b47c00fa2f3e0f27358e91977e79b7be' 
  AND token = '33qT5HvVesDKcaMvkMfGM+/12OouVvDA3zo4HjJ026c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}