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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74d6bf1d60325ee9af759a44ed3e68b29e72c1d2445bf162b659826c9e67a00d' 
  AND token = 'ky0FLQstalm8DN7f0tazTBKR22lIQtT4mOKZ3CVLnEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}