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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '427365cc38f5b7030b432a14cba3cc0ac9e76c8944bad7250925f436d4701bbb' 
  AND token = 'aZXc8Un36QW+rHKcuMUhzoa4G0Do0o22vl/EnpWWrKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}