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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a8328ecc1c67c5f60315c9d7547db08aef16ff486502bad456577132d972e4d' 
  AND token = 'uAZXG0H+0zDkb1t0G2BxPBw6lqroYar+p333XIuXdZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}