SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d66801ccdf9ecc376d936ccf3f3e68275e0feff200f9c934ba23f10bf6afc4d' 
  AND token = 'Dib6DAPG1B+m2x3FjjEyoCYdMgeW8b42aFdlCM0z7VE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}