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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a353760534f2f8f3f86a35569a030c5c02873e3ea999d845872badc28392f9e' 
  AND token = 'Glt1t9nbKw4rhJRrBBrcrboTqk0md/aNmgCWvE0fF18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}