SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14f71589780e41c088ff8f85c474ec80cafc34142379a937684f71208cf67672' 
  AND token = 'pBWcNbDKlU47cMVT6Wmnp/ynms9GhF8VvWr9xBu95ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}