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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c3a64baab045d57db58dd3360c6b0acd5b8f0273bff189ffc2d421e789f830c' 
  AND token = '+NPiE0eFwNuCG0YRJw/e69EcsggPyvbkNn3v1EAJwz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}