SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '363f81505c72c9d71746662797807c8df34d9ac0b03ca6e16fff7b378ac2afad' 
  AND token = '7TAGH+oB2UJPojm2/9707gdV9PbK6WErgms0TTmxjSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}