SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3ad52348dc5ca562e74d2a18a8cadf2c3b531a99417f2cff087dff56bb3acbd' 
  AND token = '3F0b1XuRxqL27jRQUqh4hT2fI2jMJPLp4a3BS3/2nUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}