SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d1d708b9625cbf6569a81bc6ed215c175359fd8c9fe81c31cf8b11ab81deccd' 
  AND token = '6TLRq/G9OMJCx//hjcuDFokiQf8NTjnME5KyLAQFUVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}