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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e8b097f8b61a29f4f2bafc35d28abe4dba083a07a59933f751e27dd58f595e7' 
  AND token = '3De0GFTYFslGC9KXlLK+At1uKiOEA/SQq1aXdO9Cuos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}