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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b63c4088a01fcbb900d03ca60fa234138041ebf387f7f74cc7fb63816873a43f' 
  AND token = 'VQeFvdt2a+hzTgzZE819krAUoCnL8S6DJqChcn4qbUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}