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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a91cf6170e332af0f98f1d06649ee76e13b9b5f3184f9c083170ece70b224693' 
  AND token = '49uiqiWTeDMOFIVpHF9SBhtb8yOh1XHlDPKR/k/KgIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}