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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4ba1c3ff0dbdc746cf54554b0823ecdf59c43c82cbfd0dd510a2790748cc4ac' 
  AND token = '46+NYc4p8WeMfcg7WKJEFXUyuA5Nf1eb6q2PRWzfg5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}