SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '182caf843bdc004ccf4db41cbdeab4baaa738357fca9ca0260ec4b22bb3b268f' 
  AND token = 'VJK8UR0gndqFoebrD0/Fo+ZzYgWg5Tw9WHJpAC5Pls8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}