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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2acf60fb2e014b4f7dfcdd2b6e26c4ea00e8699547fbf5bb2a598c39156a8414' 
  AND token = 'AsjKDEakkN5NtggjvP2RcXcAg8X8V72I0rhWzppjQn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}