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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef2f4321eefee4a3bbd23c432f10dde93699260a5a53d43bf299eae792ee3a71' 
  AND token = 'xB8UCV4DOd3VFFFTQnPeAx/Tl93sJqoRHgqfxTeGwB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}