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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dea3022aaf00cc97f59654c94d371bb60a7f946ec6f01b6ff5f75291b0b1b79' 
  AND token = 'pBps4UxxL8uCtO8EQegq/CTnc7S7ZQqUjv2n+DPmxTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}