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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35025f11d653b5e100f51bba63c97874f446cae68f7dcd717c4bb5dfe9a8eff8' 
  AND token = '9gOvaGVVIfSj/h+NP3CreLRUvG52A2+AADg6byqIE0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}