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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53da1e9c79db0b42c1d8d865a667ae8074b94f7c90a1ef059d669e44dcfa36c0' 
  AND token = 'bwV6WtxFdra4y2kW5ftNS+gHZ8xJGlR5jBPfb5Vmzf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}