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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9650943553c9f43bc189ff0c518cd7b51d98766a589d0d6a0d8420249c6da82f' 
  AND token = 'MoeYVR2vQvWf1Kxt/Fx+QSuCaEUpuyf+fA3R/4VWBkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}