SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04e4d4a5fdf148026572d17175900c1f74050bb1228cb12d99d911eb0fecbb32' 
  AND token = 'pALC51SrZ/4tlBydgiEFDcoZvG2rm4W1kY7sfSWHfAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}