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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42826134a7e5cd7d01087d7a51a2624948a615f7aeb47a54b134b92da7a1a782' 
  AND token = 'h+q0fDgGpedxzFxGNbhqsLuN74SEjeYvmXeAyfit+mU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}