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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c586b19c12e298c73eff78c5f0012c398efb0a62beda3eee6436e0daf8fd9b9a' 
  AND token = 'x4NLcculcTVpfjWVfWOCOLIvM0TnuILKpu4leCxc9G4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}