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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d46ee28d08df889dccc7c7a9f9066773caaea442c288dc00d7472310b52ad78' 
  AND token = '4TOP+CF1qTK5CctdPfynw+dw3FKzNhF7AtM3mo7e8gM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}