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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3532e43e3973f3c7576d83247f7e57ffbe4dcf8132d98226b821f96aebf0a026' 
  AND token = 'VTxEtnito6NbBIkpYWnceuCtIgM5pEjY4c2m8UDfuJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}