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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7017ca4246299db801300f3cc72430d3fab6aa78ca28807d66a920caaf25d4af' 
  AND token = 'OmvcNRgWmdOXZqYX2VpTRUXt6D5xdlg0SKreYSUxBrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}