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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b485cdcfc7d00e404c58a161652084fd316ea4a60022abca3cedc986d69abd18' 
  AND token = 'OWybEsNERTkkG0VZU4TdjwByvRrFOk5/XhhPQ392HCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}