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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b4fa06ead52d0a45c28ede95f4ff5c1577ef402ba649c9fa369fb3c290d789a' 
  AND token = 'M7tzYFp+cd0zklD7Mv4QTOoF9Dg90QKIncUS/GeL0EA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}