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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60f7a1cb49a965ca5c91a10140a776feed53cc69e48570e54096b83dc59d4fdf' 
  AND token = '25vPVf2aM3BV4qbFc3jg2pPOIsHUNEV/pTbxvkl1Ph0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}