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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3a581e6d4afa4be7d478d24145d4a7b131e8afc54d9804ce605fcb2a6985bf8' 
  AND token = 'vqIZX1T+12nRV1DWFvzn94S/ATVFDO3PDSbI1XJjoKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}