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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4064769c857698e6097acb83c7bb48f6b41011e1cf91ec9f59328a67b7cf9dc0' 
  AND token = 'jAAZ0G9Cngmi/tka7eVK/k7YZd30l+cBD43jzOfnBmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}